A Clinical Measure Sensitive to Treatment Effects
Schizophrenia Cognition Rating Scale
The Schizophrenia Cognition Rating Scale (SCoRS) is a 20-item interview-based clinical assessment available on The Pathway or via pen-and-paper that evaluates cognitive deficits and the degree to which these deficits impair patients’ day-to-day functioning. It was originally developed in 2001 at Duke University Medical Center by VeraSci CEO and Co-Founder Dr. Richard Keefe and is licensed through VeraSci. The SCoRS is used in registration-level clinical trials, academic research and in clinical settings.
The SCoRS contains questions about the patient’s ability to manage cognitively demanding, functionally relevant, everyday tasks such as conversations, watching television and using electronic devices.
The items were developed to assess the following cognitive domains:
- Working Memory
- Language Production
- Problem Solving
- Motor Skills
- Social Cognition
As an interview-based assessment of cognition, the SCoRS meets the criteria established by the FDA-NIMH-MATRICS panel for co-primary outcome measures for cognitive enhancement trials in schizophrenia.