American Society of Clinical Psychopharmacology
Hollywood, Florida, June 16-19


  • Assessment of functional capacity is important in the development of treatments for cognitive impairment and may be a part of the overall clinical evaluation in patients with schizophrenia and other CNS disorders. • The Virtual Reality Functional Capacity Assessment Tool (VRFCAT©) is a computer based virtual-reality measure of functional capacity that uses a realistic simulated environment to recreate routine activities of daily living. • The VRFCAT contains the components of a shopping trip, including searching the pantry at home, making a list, taking the correct bus, shopping in a store, paying for the purchases, and getting home. • Previous pilot studies indicated that the assessment of functional capacity with virtual reality methodology is feasible, and suggested such a tool may meet criteria for use as a co-primary measure. • The VRFCAT, MATRICS™ Consensus Cognitive Battery (MCCB), and the UCSD Performance –based Skills Assessment (UPSA-2-VIM) were administered to a sample of people with schizophrenia to examine the validity, sensitivity, and reliability of the VRFCAT and concurrent validity. • These data were also collected on healthy controls to examine discriminant validity.

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