WCG VeraSci is pleased to share results from a recent study examining the feasibility and reliability of remote, in-home self-administration of cognitive tests using the Pathway ePRO platform.

Sixty-one older adults with and without subjective cognitive decline completed remote and in-person testing using self-administered versions of select cognitive tests within the Brief Assessment of Cognition (BAC). Remote and in-person testing sessions were completed approximately 1 week apart, with half of all participants completing the remote testing first.

Results were compelling and suggest that remote cognitive testing is feasible, reliable and sensitive to objective cognitive impairments in individuals with subjective cognitive decline. In all but one cognitive domain assessed, measures of test-retest reliability (absolute agreement ICCs) across settings exceeded .7, even for tests employing alternate forms. No differences between remote and in-person testing were observed for measures of processing speed (BAC symbol coding), visuospatial working memory or verbal fluency. Comparisons between participants with and without subjective decline demonstrated significant and reliable differences between groups that were reliable across remote and in-person settings.

Initial results of this study were presented at the 14th Clinical Trials on Alzheimer’s Disease (CTAD) November 9-12, 2021. The poster presentation is available here.

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